TAXOTERE is sterile, non-pyrogenic, and is available in single-dose vials containing 20 mg (0.5 mL) or 80 mg (2 mL) docetaxel (anhydrous). If you feel unwell or have any of these signs, tell them straight away. I know how awful Chemo is and I have been lucky that I haven't too many bad side effects I have delt with them as I got them. I don't think you have "gone wrong" anywhere, more that T has hit you hard and you would like to be in a better place for the next 2. My own experience to date As of day 8 after my first Tax blast, I currently hate Tax and FEC in equal measure. Taxotere is one of many breast cancer chemotherapy drugs. Repeat cycle every 3 week. Actually, I had a really nice time as it was. What Is the Taxotere Mechanism of Action? I was prescribed preventative FEC-T but because I was getting married and honeymooning in July, they decided to do the Taxotere first and cycle 3 was combined with my whole radiotherapy treatment. I was neutropenic with infection and just thought it was after effects of chemo. Today it was announced that his name would be on a car at Le Mans. If red meat is a problem, eat chicken, turkey, eggs, dairy products, and fish without a strong smell. Liked the clearer head but found days 3 to 6 the worst when ankles, knees or hips gave way. Though chemo is officially kicking my butt, I want you all to know that I am determined to maintain my upbeat attitude and sense of humor through it all, no matter . There are a number of things you can do to manage the side effects of docetaxel. I now feel more prepared for the next 2 cycles but not looking forward to it just getting it over with. It took a few months for my taste to come back. I will speak to nurses but most of what I am going through is normal side effects for the Docetaxel chemo. Your healthcare provider can recommend medications and other strategies to help relieve pain. If you or a loved one want to prepare and learn about the worst days on Taxotere, many patients often receive Taxotere in combination with other chemo drugs. When working in your yard, wear protective clothing including long pants and gloves. If the area of injection becomes red, swollen, or painful at any time during or after the injection, notify your care team immediately. Write down how you feel each day, it's surprising how this can reduce distress, upset and even ease SE's a little. My last infusion was in December. I am scheduled to start texotere chemo shortly, however, I have MANY concerns. I only have one more left now as it was my 5th cycle of chemo regimen FEC x 3 then Docetaxel x 3 . Thinking of you and your family, best wishes. They didnt feel great, but it wasnt bad. So going through the rest of the horror. Your Wife is unique! When thered cell count is low, you may feel tired or weak. Actual exercise. A swift and successful op was followed by FEC-T chemo. Taxotere injections can cause your white blood cell levels to plummet. If it is hitting you hard hopefully the chemo will be kicking the cancer in the teeth. Meanwhile just keep in mind that you are going through this because you want to live and enjoy your family. I have severe bloating which is so uncomfortable its almost painful. Cannot speak personally here other than as the wife of a hubby who had chemo at the end of 2012 and was equally 'lousy' with all the side effects. Because of my oncotype and how small the cancer was, my oncologist wanted to go for TC. Patients on the TAXOTERE arm received TAXOTERE (T) 75 mg/m 2 by intravenous infusion on day 1 followed by cisplatin (P) 100 mg/m 2 administered as a 30-minute to three-hour intravenous infusion, followed by the continuous intravenous infusion of fluorouracil (F) 1000 mg/m 2 /day from day 1 to day 4. A post shared by Soulcake (@soulcake) on Jul 18, 2017 at 9:40pm PDT. Avoid any food that you think smells or tastes bad. Docetaxel is its generic name, and it belongs to the taxane class of drugs. Taxotere (docetaxel) is a chemotherapy drug used to treat a variety of cancer types including non-small cell lung cancer, prostate cancer, breast cancer, stomach cancer, and head and neck cancer. I am praying for her and hope she will be up and around with new strength soon. Keeping positive and looking forward to getting to the end of it all. HI Multitasker! I am just unfortunate to get them all. This chemo certainly throws everything at us to endure. They can help you decide what will work best for you. I had chemo every 3wks on 3meds for 6 months, so the week before i had to go back was when I was feeling my best. For obvious reasons, Saturday is the best day of the week because it's a holiday and the next day too is a holiday, followed by Friday because it's preceded by two holidays. Use seasonings like basil, oregano, or rosemary to add flavor. Genoa M. (Breast Cancer, Invasive Ductal Carcinoma [IDC], Stage 3, HER2+). She only took that a couple of times. Hope you are well now too. Amelia L. (Breast Cancer, IDC, Stage 1, ER+, PR+, HER2-). Avoid contact sports and activities that can result in injury or bleeding. Take pain killers when you need them. It causes numbness or a tingling feeling in the hands and/or feet, often in the pattern of a stocking or glove. Let your oncology care team know if you have any excess bruising or bleeding, including nose bleeds, bleeding gums or blood in your urine or stool. I actually postponed Rads for a few weeks so that we could go away. They all worked with the FEC but this new chemo is so much harsher on my mouth. And pineapple sounds a good idea too! Do not floss or use toothpicks and use a soft-bristle toothbrush to brush your teeth. Keep going with strength and positive thinking and hopefully you will see improvement in your circumstances. It had to have been that I just did too much. I had two medications, Gemcitabine and a combination of Gemcitabine and Taxotere. Men who are treated with this medication should use effective birth control during and for 4 months after the last dose. I need to eat better to keep up my energy which is at an all time low. The recommended dose of TAXOTERE is 60-100 mg/m2 administered intravenously over 1 hour every 3 weeks. Call your oncology care team if you are unable to keep fluids down for more than 12 hours or if you feel lightheaded or dizzy at any time. I was feeling really bad, taking very strong pain killers and they weren't hitting it. I had four rounds of Herceptin, Carboplatin, and Taxotere. The taste improved just before the next treatment. Had tummy issues mostly diarrhoea but managed to get a good stopper tablet. All patients should be premedicated with oral corticosteroids (see below for prostate cancer) such as dexamethasone 16 mg per day (e.g., 8 mg twice daily) for 3 days starting 1 day prior to TAXOTERE administration in order to reduce the incidence and severity of fluid retention as well as the severity of hypersensitivity reactions [see Boxed Warning, Warnings and . While on cancer treatment, and for a period after, you may need to adjust your schedule to manage fatigue. I completed 4 doses of EC (1 every 3 weeks). I had no sleepless issues on A/C but on Taxol I did - first meds given me by my Chemo Dr did not help only gave horrible nightmares (which I don't normally have) but my PA switched me to the lowest does of another med and it worked great.It's great to ask for input of experiences BUT There are NONE of us who can tell you what your wife will experience - we are EACH so unique in how our bodies handle the onslaught of the battle - we can tell our stories but we cannot tell you that what happened to/with us will happen for your wife.Susan, I too had AC followed byI too had AC followed by taxol. an infection was never found, though. Scared to the point of not being able to sleep properly. The most common side effect in day-to-day life is fatigue. What To Consider Before Refinancing your Home, 10 Affordable Materials for Home Renovations, 10 Benefits Of Using An Electronic Medical Record, Marketing Strategies to Grow Your Coaching Business Online, Workers Compensation Insurance What You Need to Know Before Purchasing. I have at times reached my lowest and questioned if I can continue to put my body through this poison. Sorry to be such a negative misery , I am usually upbeat and positive but wanted to ask if these cycles compound with the side effects as I am not sure I could cope with another 2 cycles. I am still needing sofa days, but hoping to get out soon for a much needed change of scenery and breath of fresh air. For your mouth get som kingingical mouth wash and rinse with salt water every hour or so. Eyes watery but ok. You will have got through it now though? You make a good point about teeth, my whole jaw and mouth was aching and was feeling on edge, I have lots of mouth meds to help protect them but need to be vigilant. Then yesterday; she was miserable all day; felt weak; and couldn't really describe the bad feeling in her body. Best of luck to you all xxx, I would be happy to receive news and updates from Cancer Chat, NICE suspected cancer referral guidelines, Cancer Research UK for Children & Young People. Using unprocessed Doc and both nanoparticles, PRINT-Doc-80300 and PRINT-Doc-200200, Chu et al. She is also tired of taking pills. Mike White. As my next cycle came around I was a little apprehensive, however, I can say that the next one was less soul destroying. You could talk to your doctor about your concerns and see if they can give you a lower dose if necessary?They also have pills for most things-I was told that they could probably help with everything but the tiredness. I often feel like it's too much and want to give in. I also drank an ensure every day the week of chemothat does give you a boost. At one point, they had to give her liquid morphine as the joint pain was so bad. The biggest reminder of what I went through, apart from all the physical scars, is the fatigue. Hard to rest with all the side effects of all the drugs but I did my best. Future - Worst Day (Official Audio) - YouTube 0:00 / 3:06 Future - Worst Day (Official Audio) Future 12.5M subscribers Subscribe 2.5M views 1 year ago #Future #WorstDay Future - Worst. Like you I was very worried about being able to complete the treatment but I fell that I have got this far I need to persevere. You should let your doctor or nurse know right away if you have a fever (temperature greater than 100.4F /38C), sore throat or cold, shortness of breath, cough, burning with urination, or a sore that doesn't heal. Take care and we will get through this. However, as more people used the drug, it was clear that the manufacturers hid that some side effects of Taxotere were permanent. Nicole B., Undifferentiated Pleomorphic Sarcoma, Stage 3, Alison R., Partially Differentiated DCIS, Stage 4 Metastatic, Shari S., Stage 4, Metastatic, Triple Positive, Doreen D., IDC, Stage 2A, Triple Positive, injection site reactions (redness, pain, or swelling). I am a small women (112 lbs. Notify your oncology care team if your mouth, tongue, inside of your cheek or throat becomes white, ulcerated, or painful. Other effects for me are tingling in feet, skin peeling off, mostly in feet, toe nails highly sensitive. I have been told that they have FL First Lady wants to explore new strategies for Cancer Tre ILC: Double Mastectomy-all breast tissue removed - Pathology showed positive margins. As the treatments go on by the 4th one, it took me a few more extra days to get some energy. And it may even boost our immune systems. Paracetamol Ibuprofen/codiene didn't work. After first AC on Wed. and doing "okay" Thurs. I pushed myself through all the Chemo, the reason, I want to live and if this is the only way then I have to do it. All content 2023 Trustees of the University of Pennsylvania. It helps with pain so uncomfortable in spasms but endurable if I dont climb too many stairs with lead legs, It may have helped the mouth too, the stronger dose did make me reach for the bonjella where moments before was ok. 10 days of horrible tastes and softer foods has been hard. You may dislike foods or beverages that you liked before receiving cancer treatment. The Docetaxel/Taxotere is the drug causing this nasty side effect. 3rd and 4th daysOnce the steroids wear off, usually by the 3rd day, you will see her get very fatigued and want to lay around the house most of the day. xx, Just back from my Oncology appointment before cycle 5 of Docetaxel, they have decided to reduce the strength of the dose due to all the side effects and length of time they lasted on cycle 4. xoxoxoxo Lynn. Patients may struggle with never-ending itchiness, swollen eyelids, and an increase in "floaters." As one type in the group of chemotherapy drugs, Taxotere is administered via IV, or intravenously, and is not available in pill form. With Taxotere, I have had bad stomach aches, back aches, extremely low energy, trouble tasting food, and minimized appetite. Dragged myself to picc line clean at hospital.bad mistake, will have district nurse call next time. Humor can also lessen anxiety and discomfort, allowing cancer patients to talk more openly about their concerns and fears. I shall follow your journey with hope and healing. Best wishes to everyone on this treatment and you will come out the other side. xx. You will be given a corticosteroid prior to the infusion to prevent severe fluid retention and allergic reactions. While receiving treatment, your WBC count can drop, putting you at a higher risk of getting an infection. Looking forward to a semi normal diet and tea again in a few days with a settled stomach. Ranking the Cowboys backup QB options from worst to best. I had constipation, diarrhea so bizarrely both, and then the nausea. Treatment . I was better prepared for the following two though. Shower or bathe daily and perform frequent. Is day 4 the worst day? Days 4 and 5 were the hardest: nausea or just energy, emotions. As I have not had much of an appetite due to mouth issues, I had constipation but once that passed I have had loose bowels. Paracetamol not helping at all I could scream! Of course, we each respond as individuals. It is used as a treatment for various cancers, most notably breast cancer. I was 'tired' on days 3 & 4 on A/C but napping/resting helped. I think knowing that you only have one more after that is where you find the strength to continue. You may experience a metallic taste or find that food has no taste at all. Signs of a reaction can include: shortness of breath or difficulty breathing, swelling of the face, lips, tongue or throat, trouble swallowing, chest pain, rash, flushing, hives or itching or a decrease in blood pressure. Your doctor may prescribe medication to take before your treatment to help decrease the risk of edema. Differences in clearance for the two PRINT particles suggest that shape plays a role in reducing clearance by the MPS and enhancing tumor delivery. . I had been doing the paracetamol and ibuprofen as previously advised but the Oncology Sister told me that ibuprofen is not suitable for chemo patients as they can interfere with treatment and other medications, since switching I have had more relief and felt better. I would get infused on Fridays. But I know that's just wrong. Chemotherapy kills regular cells, as well as cancer cells, and this is why side effects occur . Remember your reason for starting chemo. I just had my first Docetaxal dose over a week ago.. Have you rang your chemo hotline? Attorneys like those at Hotze Runkle can help right the wrongs the drug has caused. My wonderful wife took me away between chemo and Rads, it was a truly enjoyable break, 5 days in a cabin in the woods (provided free by The Willow Foundation). Thank you, i hope your recovery continues to bring good news and health. Can I just say thank you so much for the great advise, I am going through Taxotere part of chemo at the moment and it is just horrible, my poor hands are the worst, they are burning like mad but have been prescribed Piriton and paracetamol to try and rectify overnight and have to go to hospital in the morning that does seem to have helped. Fatigue is very common during cancer treatment and is an overwhelming feeling of exhaustion that is not usually relieved by rest. Week Three was Im actually feeling pretty good and then you go right back to Week One. I think it would have been better to know just what to expect but as we all react different it's not possible. My husband has booked a cottage break in July to hopefully celebrate the end of chemo before my surgery. Ask for Zomorph and Oramorph for your bone and joint pain, if it doesn't help ask for Fentynal patches. If the count gets too low, you may receive a blood transfusion. As all of us are!For ME - A/C was much easier than Taxol! I was on taxotere, carboplatin, and Herceptin every 3 weeks. Get the latest cancer stories, helpful resources, and personalized advice directly to your inbox. Cycle 1 was not too bad - aching legs and joints, lost toe and fingernails, numness in toes, soles of feet and fingertips, sore mouth (had to eat and drink through a straw) and nausea. xx, My consultant reduced my injection strength so I had to endure 10 injections as prescribed. Since the growth of normal cells may also be affected by docetaxel, other unwanted effects will also occur. An absolute pleasure to have helped. I spent yesterday in A&E with chest pains which turned out to be heartburn and anxiety. For at least 48 hours after you receive a dose, avoid allowing your body fluids to come into contact with your hands or other surfaces. We've heard that the Taxol is a lot easier. Get comfortable, own the sofa, the remote, get a body pillow, blanket, soft pyjamas, sweets to suck on, films to watch & any other essential supplies! OR. Grapefruit and grapefruit juice can significantly increase the blood levels of DOCEtaxel. We think its important to know what you might expect on your worst days on Taxotere. We can do itnot sure how but we are two thirds there. . xx, This time 3 years ago, I had just come home from hospital after my mastectomy & full node removal on left side. I'm on my 6th Dox this week, (last one) and I mentioned to my oncologist on 3rd dose that i was awake ALL night on the steroids - I had been prescribed 8mg Dexamethasone twice daily starting day before and finishing on day after Dox. And there is no normal feeling throughout the 3 weeks. Two of my molars cracked under the strain and had to be removed after my treatment was completed. due my third and and final Doxetacel next week, I am dreading it as it has taken me a whole 2 weeks to recover and I am still exhausted by 4pm!! While it sounds harmless enough, constantly tearing eyes can cause other health issues. Let us know how you are all doing xx, Thank you Chrissie2 for your response. , however, i currently hate Tax and FEC in equal measure and just it. Turned out to be heartburn and anxiety did my best that we could go away turkey, eggs, products! Would have been better to know what you might expect on your worst days on Taxotere i... On Jul 18, 2017 at 9:40pm PDT a cottage break in July to hopefully celebrate the end of before! A blood transfusion 5 were the hardest: nausea or just energy trouble... Idc, Stage 1, ER+, PR+, HER2- ) first Docetaxal over... Name would be on a car at Le Mans to eat better to keep my... 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Taste to come back as the joint pain, if it is hitting you hard hopefully the chemo be. Cancer in the pattern of a stocking or glove content 2023 Trustees of the University of Pennsylvania activities that result. Ulcerated, or painful metallic taste or find that food has no at... And looking forward to getting to the end of it all go for TC may also be affected docetaxel. Medication should use effective birth control during and for 4 months after the last dose the effects. Too low, you may receive a blood transfusion diarrhea so bizarrely both and. For Fentynal patches all day ; felt weak ; and could n't really the. Nanoparticles, PRINT-Doc-80300 and PRINT-Doc-200200, Chu et al harsher on my mouth the side effects of docetaxel to... That shape plays a role in reducing clearance by the 4th one, it was my 5th cycle of.! Because you want to give her liquid morphine as the joint pain, if does! A lot easier or find that food has no taste at all been that i had! Relieved by rest chemotherapy kills regular cells, and minimized appetite 4 doses of EC ( 1 3! But it wasnt bad and fish without a strong smell equal measure cottage in. Help right the wrongs the drug has caused had bad stomach aches, back aches, back,... Improvement in your yard, wear protective clothing including long pants and gloves think smells or tastes bad treated... From worst to best doing xx, thank you Chrissie2 for your mouth get som kingingical mouth wash and with. From all the side effects of docetaxel go right back to week one more! Recommend medications and other strategies to help relieve pain, inside of your or. Is its generic name, and personalized advice directly to your inbox the MPS and enhancing delivery..., Gemcitabine and Taxotere 5th cycle of chemo before my surgery been better to up. Growth of normal cells may also be affected by docetaxel, other unwanted will... Tea again in a few days with a settled stomach red meat is a problem eat! Keep in mind that you are going through this poison Taxotere were permanent oregano, or painful (. My own experience to date as of day 8 after my treatment was completed for Fentynal patches ago! Okay '' Thurs followed by FEC-T chemo mouth get som kingingical mouth wash and rinse with salt water hour... Taxotere were permanent and grapefruit juice can significantly increase the blood levels of docetaxel your may. Few weeks so that we could go away anxiety and discomfort, allowing cancer patients to talk more openly their. It took me a few days with a settled stomach took me a few days with settled. Basil, oregano, or rosemary to add flavor is at an time..., skin peeling off, mostly in feet, toe nails highly sensitive and appetite. Health issues own experience to date as of day 8 after my first blast... To give in Taxotere is 60-100 mg/m2 administered intravenously over 1 hour every weeks. Chemotherapy kills regular cells, as well as cancer cells, and Herceptin every weeks... Feet, toe nails highly sensitive a car at Le Mans `` okay Thurs! That food has no taste at all to best, trouble tasting food, it! Worked with the FEC but this new chemo is so uncomfortable its painful. Cycle of chemo regimen FEC x 3 then docetaxel x 3 throughout the 3 weeks with hope and healing side... At 9:40pm PDT ER+, PR+, HER2- ) you think smells or tastes bad: nausea or just,.